Prof. Karen Miga University of California, Santa Cruz

The Human Pangenome Project: Creating a Reference that Better Represents Human Global Genetic Diversity

Throughout my career, I have developed innovative computational and experimental approaches to advance our understanding of centromeric and pericentromeric DNAs. I work at the forefront of genome technologies as part of the T2T and Pangenome initiative to construct genetic and epigenetic maps to expand our understanding of their structure and function. As a group leader, I prioritize fostering a creative and scientifically rigorous environment that supports inclusivity and diversity within our scientific team. I also prioritize training that operates at the intersection of science, justice, and equity.

Dr. Davide Cirillo Barcelona Supercomputing Center

Synthetic Data in Biomedical Research: From Knowledge Discovery to Knowledge Generation

Davide Cirillo is the head of the Machine Learning for Biomedical Research Unit and Juan de la Cierva Incorporación fellow of the BSC Computational Biology group. His area of expertise is data analysis and predictive modeling for precision medicine using network biology and machine learning. His research in precision medicine includes rare diseases and paediatric cancers, as well as ethics of artificial intelligence. He is co-editor of the book Sex and Gender Bias in Technology and Artificial Intelligence: Biomedicine and Healthcare Applications (Elsevier Academic Press 2022).

Dr. Elisabeth Bik Harbers Bik LLC

Errors and Misconduct in Biomedical Research

Elisabeth Bik, PhD is a Dutch-American microbiologist who has worked for 15 years at Stanford University and 2 years in industry. Since 2019, she is a science integrity volunteer and consultant who scans the biomedical literature for images or other data of concern. She has found over 8,000 scientific papers, and her work resulted in over 1,200 retractions and another 1,000 corrections. For her work in science communication and exposing research misconduct, she received the 2021 John Maddox Prize.

Ahmad Alkhan University of Limerick

Deep Learning approach for detecting and segmenting Perineural Invasion in Colon, Prostate, and Pancreatic cancers

Stefanus Bernard SFI Centre for Research Training in Genomics Data Science

Bioinformatics Refinement of CRISPR-Cas9 Knockout Screens Reveals Additional Genes Modulating Cellular Responses to CDC7 Inhibitors

Elle Loughran Trinity College Dublin

Factors in the Development of Extreme Ploidy States in Cancer

Linda Smith University College Cork

A novel approach to Caudoviricetes taxonomy utilising whole proteome structure-structure comparison

Anna Grossbach School of Mathematical and Statistical Sciences, University of Galway

Mapping Genetic Determinants of DNA Methylation Across Early Development

Catherine Higgins University College Dublin

Clustering imbalanced functional data - enhancing the clustering accuracy of time-course gene expression data

Mariagiovanna Pais Queen's University

Exploring endocrine disrupting pathways using knowledge graph and network biology.

Metin Yazar School of Computer Science, University College Dublin

Unravelling Resistance Mechanisms to Synthetic Lethal Therapies in Cancer Through Protein-Protein Interaction Networks

Pouya Motienoparvar University of Galway

A genetic network integrates regulation of the vegetative-reproductive phase transition in Arabidopsis thaliana

Emma Corley Clinical Neuroimaging Laboratory, Centre for Neuroimaging, Cognition, and Genomics (NICOG), University of Galway, Ireland

Associating Mood Symptom Severity with Subcortical Brain Volumes in Bipolar Disorder and Major Depressive Disorder using an Item Response Theory Model

Javier Villegas Salmerón Royal College of Surgeons in Ireland

Characterization of the mouse intra-amygdala kainic acid model at single-cell resolution reveals cell-type specific contributions to epilepsy phenotype

Sophia Heneghan School of Pharmacy and Biomolecular Sciences, Royal College of Surgeons in Ireland

The impact of copy number variants in diagnosis and severity of autosomal dominant polycystic kidney disease

Nicole Glendinning School of Biological Sciences, and Institute for Global Food Security, Queen’s University Belfast

DNA Methylation in Vulnerability to Opioid Use Disorder

Karen Guerrero Vazquez University of Galway

Predicting Age and Identifying Aging-Related Genes from Muscle Gene Expression Data

Roofiya Koya University College Dublin

Mechanistic insights into long noncoding RNAs through high resolution analysis of tumour mutations.

Aideen McCabe School of Biochemistry and Cell Biology, University College Cork

Understanding Ovarian Cancer: Lessons Learned from Cells, Apps and Patients

Hannah Nyarko Royal College of Surgeons in Ireland

Assessing the spatial patterns of immune and stromal cells for prognosis in early-stage ER+/HER2- Breast Cancer

Micheál Ó Dálaigh School of Biological and Chemical Sciences, University of Galway

Kinnex Long-Read Resequencing of Acute Myeloid Leukaemia Single-Cell RNA Samples for Improved Detection of Malignant Genomic Alterations

John-Paul Wilkins Queen's University Belfast

Secrets in the Sewers - Revealing the hidden diversity of SARS-CoV-2 in Northern Irish wastewater

Kate Ryan Antimicrobial Resistance and Microbial Ecology (ARME) Group, School of Medicine, University of Galway

Genomic identification and characterisation of novel bacterial species from Space Craft Assembly Clean Rooms

Emmet Campbell Queen's University Belfast

In silico phage-bacteria infection networks (PBINs) of Streptococcus suis reveal co-evolution patterns between host and prophage

Anna Tumeo University of Galway

Validation of a field-deployable automated DNA extraction system as a tool for assessment of microbial diversity in marine ecosystems

Olivier Dennler School of Medicine, University College Dublin

Evaluating Sequence and Structural Similarity Metrics for Predicting Shared Paralog Functions

Sophie Matthews University of Galway

Variable gene copy number in cancer-related pathways is associated with cancer prevalence across mammals

Maria Eleonora Rossi School of Biological and Chemical Sciences, University of Galway

Independent origins of spicules reconcile the evolutionary history of sponges (Porifera)

Nicholas Dimonaco Queen's University Belfast

PyamilySeq: Transparent and interpretable gene (re)clustering and pangenomic inference across species and genera highlights the fragility of conventional methods

James McInerney University of Liverpool

panGPT: An AI transformer for generating large pangenome models.

Michael Lynch School of Medicine, Limerick Digital Cancer Research Centre, Health Research Institute (HRI), University of Limerick

Supervised multimodal demultiplexing outperforms conventional demultiplexing of scRNAseq

Seyed Aghil Hooshmand School of Mathematical and Statistical Sciences, University of Galway

Advancing Cancer Research through Integration of Liquid Biopsy Data in cBioPortal: Insights from the All-Ireland Cancer Liquid Biopsies Consortium (CLuB)

Yezhao Zhong University of Galway

Adverse Drug Reaction Profile Prediction: Denoising, Signal Enhancement and Missing Row Imputation